LY6G Monoclonal Antibody, Biotin [YRmLy-6G] (CPAB0451)
- SKU:
- CPAB0451
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Rat
- Isotype:
- IgG2a
- Clone:
- YRmLy-6G
- Applications:
- IHC
- FC
Description
LY6G Monoclonal Antibody, Biotin [YRmLy-6G] (CPAB0451)
The LY6G Antibody (Biotin) (CPAB0451) offered by Assay Genie is a valuable tool for researchers studying the LY6G protein, a marker of neutrophils and a critical component of the immune response. This polyclonal antibody, produced using rabbits, is highly specific to human samples and has been validated for use in immunohistochemistry applications. It binds specifically to the LY6G protein, allowing for precise detection and analysis in a variety of cell types.LY6G is an important protein involved in the regulation of inflammatory responses and plays a key role in the recruitment and activation of neutrophils in the immune system.
Research into LY6G has implications for understanding immune function in various diseases, such as infections, autoimmune disorders, and inflammatory conditions. The LY6G Antibody (Biotin) is a valuable tool for researchers looking to investigate the role of LY6G in these contexts and develop potential therapeutics targeting this protein.
Product Name: | LY6G Antibody, Biotin |
Product Sku: | CPAB0451 |
Size: | 500μg |
Host Species: | Rat |
Immunogen: | Ly-6G-transfected cell line. |
Clone: | YRmLy-6G. |
Reactivity: | Other bodies |
Applications: | Immunohistochemistry, Flow Cytometry |
Purification Method: | Protein A column. |
Isotype: | IgG2a |
Background: | Myeloid differentiation antigen Gr1 (Ly6G) is a GPI-anchored protein, which is briefly expressed on monocytes in the bone marrow. The level of the Ly6G expression in the bone marrow completely correlates with granulocyte differentiation and maturation. Ly6G ligation on murine neutrophils inhibits neutrophil recruitment, thus providing the first evidence of a function for the Ly6G molecule. Ly6G is seen primarily on neutrophils, also in a subgroup of eosinophils, differentiating pre-monocytes and plasmacytoid dendritic cells. |
Synonyms: | Lymphocyte antigen 6G, Ly-6G, Ly-6G.1, Ly6g, Gr1, Gr-1. |
Storage Buffer: | In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |