The LuxS Antibody (PACO35202) is a polyclonal antibody specifically designed for research involving LuxS, an enzyme involved in quorum sensing and bacterial communication. This antibody is raised in rabbits and is highly reactive with LuxS protein in a variety of samples, making it ideal for use in Western blot applications. By binding to LuxS, this antibody enables the detection and analysis of LuxS in different cell types, allowing for detailed studies in microbiology and bacterial communication.LuxS is a key enzyme in the production of autoinducer-2 (AI-2), a molecule involved in inter-species bacterial communication.
Understanding the role of LuxS and AI-2 signaling is crucial for research into bacterial behavior, biofilm formation, and pathogenicity. This antibody provides researchers with a valuable tool for studying LuxS and its functions in various bacterial species, offering insights that can help advance our understanding of microbial interactions and develop new strategies for combating bacterial infections.
Antibody Name:
luxS Antibody (PACO35202)
Antibody SKU:
PACO35202
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:1000-1:5000
Species Reactivity:
Escherichia coli
Immunogen:
Recombinant Escherichia coli S-ribosylhomocysteine lyase protein (2-171AA)
Western blot. All lanes: luxS antibody at 2µg/ml + DH5a whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 20 kDa. Observed band size: 20 kDa.
Background:
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
Synonyms:
S-ribosylhomocysteine lyase (EC 4.4.1.21) (AI-2 synthesis protein) (Autoinducer-2 production protein LuxS), luxS, ygaG
UniProt Protein Function:
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
UniProt Protein Details:
NCBI Summary:
Escherichia coli luxS is capable of inducing V. harveyi luminescence. [More information is available at EcoGene: EG12712]. LuxS is involved in biosynthesis of autoinducer, the hormone-like signal that mediates cell-cell communication during quorum sensing, the response to increased cell density . [More information is available at EcoCyc: EG12712].
