SSB Rabbit Polyclonal Antibody (CAB0630)
- SKU:
- CAB0630
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SSB Rabbit Polyclonal Antibody |
SKU: | CAB0630 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 166-408 of human SSB (NP_003133.1). |
Sequence: | KFVE TPGQ KYKE TDLL ILFK DDYF AKKN EERK QNKV EAKL RAKQ EQEA KQKL EEDA EMKS LEEK IGCL LKFS GDLD DQTC REDL HILF SNHG EIKW IDFV RGAK EGII LFKE KAKE ALGK AKDA NNGN LQLR NKEV TWEV LEGE VEKE ALKK IIED QQES LNKW KSKG RRFK GKGK GNKA AQPG SGKG KVQF QGKK TKFA SDDE HDEH DENG ATGP VKRA REET DKEE PASK QQKT ENGA GDQ |
Tested Applications: | WB IHC-P IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:100 - 1:500 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | La; LARP3; La/SSB; SSB |
Positive Sample: | Jurkat,LO2,HepG2,293T |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 47kDa |
Observed MW: | 47kDa |
The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein.
Purification Method: | Affinity purification |
Gene ID: | 6741 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |