The Lumican Rabbit Monoclonal Antibody is a valuable tool for researchers studying the role of the Lumican protein in various biological processes. Lumican is a member of the small leucine-rich proteoglycan family and is involved in extracellular matrix organization and cell adhesion.This antibody, generated in rabbits, exhibits high specificity and sensitivity for Lumican in human samples. It is suitable for use in applications such as Western blotting, immunohistochemistry, and immunofluorescence, allowing for the detection and analysis of Lumican in different cell types and tissues.
With Lumican implicated in conditions such as cancer, inflammation, and fibrosis, understanding its function and regulation is crucial for the development of potential therapeutic strategies. The Lumican Rabbit Monoclonal Antibody provides researchers with a reliable tool to further investigate the role of Lumican in these disease processes, ultimately advancing our knowledge in the field of molecular biology and potentially leading to the development of novel treatment options.
Product Name:
Lumican (LUM) Rabbit Monoclonal Antibody
SKU:
CAB11593
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 212-338 of human Lumican (LUM) (NP_002336.1).
This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair.
Purification Method:
Affinity purification
Gene ID:
4060
Clone Number:
ARC0637
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Lumican (LUM) (LUM) Rabbit mAb (CAB11593) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
