Lumican (LUM) Rabbit Polyclonal Antibody (CAB5352)
- SKU:
- CAB5352
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Lumican (LUM) Rabbit Polyclonal Antibody |
SKU: | CAB5352 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-338 of Lumican (LUM) (NP_002336.1). |
Sequence: | QYYD YDFP LSIY GQSS PNCA PECN CPES YPSA MYCD ELKL KSVP MVPP GIKY LYLR NNQI DHID EKAF ENVT DLQW LILD HNLL ENSK IKGR VFSK LKQL KKLH INHN NLTE SVGP LPKS LEDL QLTH NKIT KLGS FEGL VNLT FIHL QHNR LKED AVSA AFKG LKSL EYLD LSFN QIAR LPSG LPVS LLTL YLDN NKIS NIPD EYFK RFNA LQYL RLSH NELA DSGI PGNS FNVS SLVE LDLS YNKL KNIP TVNE NLEN YYLE VNQL EKFD IKSF CKIL GPLS YSKI KHLR LDGN RISE TSLP PDMY ECLR VANE VTLN |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | LDC; SLRR2D; Lumican (LUM) |
Positive Sample: | A-549,HepG2,Mouse heart,Mouse lung,Rat heart,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted, extracellular matrix, extracellular space. |
Calculated MW: | 38kDa |
Observed MW: | 50-100kDa |
This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair.
Purification Method: | Affinity purification |
Gene ID: | 4060 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |