The Luc7L2 Polyclonal Antibody (CAB13096) is a valuable research tool for investigating the Luc7L2 protein, which plays a role in pre-mRNA splicing and mRNA export. This antibody is produced in rabbits and has been validated for use in Western blot applications, where it specifically binds to the Luc7L2 protein.Luc7L2 is involved in regulating alternative splicing events, which are crucial for generating protein diversity and regulating gene expression. Dysregulation of alternative splicing has been implicated in various diseases, including cancer and neurological disorders.
By targeting Luc7L2, researchers can further understand the mechanisms underlying these diseases and potentially identify new therapeutic targets.This antibody is highly reactive with human samples, making it ideal for studying Luc7L2 in clinical samples. Its specificity and sensitivity allow for accurate detection and analysis of Luc7L2 levels in different cell types and tissues. Researchers in the fields of molecular biology, genetics, and biomedicine will find this antibody essential for their studies on alternative splicing and gene regulation.
Product Name:
LUC7L2 Rabbit Polyclonal Antibody
SKU:
CAB13096
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 313-392 of human LUC7L2 (NP_057103.2).
This gene encodes a protein that contains a C2H2-type zinc finger, coiled-coil region and arginine, serine-rich (RS) domain. A similar protein in mouse interacts with sodium channel modifier 1, and the encoded protein may be involved in the recognition of non-consensus splice donor sites in association with the U1 snRNP spliceosomal subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
51631
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using LUC7L2 Rabbit pAb (CAB13096) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
