The LTBR Polyclonal Antibody (CAB5351) is a vital tool for researchers studying the lymphotoxin-beta receptor (LTBR), a crucial protein involved in immune response and inflammation regulation. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.LTBR is a key player in the immune system, functioning in the activation of NF-kappaB and MAPK8/JNK pathways, which are essential for cell survival and inflammation control. The LTBR Polyclonal Antibody enables precise detection and analysis of LTBR protein levels in various cell types, providing valuable insights for studies in immunology, inflammation, and autoimmunity.
Understanding the role of LTBR in immune regulation and inflammatory responses is essential for developing targeted therapies for a range of diseases, including cancer, autoimmune disorders, and chronic inflammatory conditions. The LTBR Polyclonal Antibody is an indispensable tool for researchers aiming to uncover pathways and mechanisms involving LTBR and its implications in disease progression and treatment.
Product Name:
LTBR Rabbit Polyclonal Antibody
SKU:
CAB5351
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 336-435 of human LTBR (NP_002333.1).
This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed.
Purification Method:
Affinity purification
Gene ID:
4055
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using LTBR Rabbit pAb (CAB5351) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
