The LTBR Polyclonal Antibody (CAB22021) is a vital tool for researchers studying lymphotoxin beta receptor (LTBR), a crucial protein involved in immune response and inflammation. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the LTBR protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for research in immunology and cancer.LTBR is a key player in the regulation of immune responses, particularly in the development and maintenance of secondary lymphoid tissues. Its role in signaling pathways related to inflammation and immune cell activation makes it a promising target for studies on diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions.
Understanding the function of LTBR is essential for the development of new therapies that modulate immune responses in a targeted manner.In conclusion, the LTBR Polyclonal Antibody (CAB22021) is a valuable tool for researchers investigating the role of LTBR in immune regulation and disease pathology. Its high reactivity and specificity make it an excellent choice for studies aiming to elucidate the complex mechanisms of immune response modulation.
Product Name:
LTBR Polyclonal Antibody
SKU:
CAB22021
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human LTBR (NP_002333.1).
This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed.
Purification Method:
Affinity purification
Gene ID:
4055
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse brain, using LTBR Rabbit pAb (CAB22021) at 1:700 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.