The LTBP3 Polyclonal Antibody (CAB15687) is a valuable tool for researchers studying the latent transforming growth factor beta-binding protein 3 (LTBP3) in various cellular processes. This antibody, produced in rabbits, is highly specific to human LTBP3 and has been validated for use in Western blot applications. By binding to LTBP3, researchers can detect and analyze the protein in different cell types, making it ideal for studies in developmental biology, tissue regeneration, and fibrosis.LTBP3 is a crucial component in the regulation of TGF-β signaling, playing a role in the activation and secretion of TGF-β.
Dysfunction of LTBP3 has been linked to various diseases, including cancer, pulmonary fibrosis, and cardiovascular disorders. Therefore, understanding the function and regulation of LTBP3 is essential for developing targeted therapies to treat these conditions.Overall, the LTBP3 Polyclonal Antibody (CAB15687) is a valuable tool for researchers seeking to explore the biological functions of LTBP3 and its implications in disease pathology. Its high specificity and reliability make it a trusted reagent for experiments aimed at unraveling the complexities of TGF-β signaling pathways.
Product Name:
LTBP3 Rabbit Polyclonal Antibody
SKU:
CAB15687
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1004-1303 of human LTBP3 (NP_001123616.1).
The protein encoded by this gene forms a complex with transforming growth factor beta (TGF-beta) proteins and may be involved in their subcellular localization. Activation of this complex requires removal of the encoded binding protein. This protein also may play a structural role in the extracellular matrix. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
4054
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of Rat uterus, using LTBP3 Rabbit pAb (CAB15687) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 45s.
