UniProt Protein Function: | LTBP1: May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extra cellular matrix (ECM). Belongs to the LTBP family. 5 isoforms of the human protein are produced by alternative splicing.Protein type: Chaperone; Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 17|17 E2Cellular Component: cell soma; cytoplasm; dendrite; extracellular matrix; extracellular region; extracellular space; microfibril; mitochondrion; perinuclear region of cytoplasm; protein complex; proteinaceous extracellular matrixMolecular Function: calcium ion binding; growth factor binding; microfibril binding; transforming growth factor beta bindingBiological Process: positive regulation of collagen biosynthetic process; transforming growth factor beta receptor signaling pathway |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q8CG19 |
NCBI GenInfo Identifier: | 1063759631 |
NCBI Gene ID: | 268977 |
NCBI Accession: | NP_001318166.1 |
UniProt Secondary Accession: | Q8CG19,O88349, Q505C9, Q8BNW7, Q8C7F5, Q8CG18, Q8CIR0 B1B1D9, B1B1E1 |
UniProt Related Accession: | Q8CG19 |
Molecular Weight: | |
NCBI Full Name: | latent-transforming growth factor beta-binding protein 1 isoform 7 |
NCBI Synonym Full Names: | latent transforming growth factor beta binding protein 1 |
NCBI Official Symbol: | Ltbp1Â Â |
NCBI Official Synonym Symbols: | Tgfb; Ltbp-1; Ltbp1L; 9830146M04; b2b1000Clo; 9430031G15Rik; TGF-beta1-BP-1Â Â |
NCBI Protein Information: | latent-transforming growth factor beta-binding protein 1 |
UniProt Protein Name: | Latent-transforming growth factor beta-binding protein 1 |
UniProt Synonym Protein Names: | Transforming growth factor beta-1-binding protein 1; TGF-beta1-BP-1 |
Protein Family: | Latent-transforming growth factor beta-binding protein |
UniProt Gene Name: | Ltbp1Â Â |
UniProt Entry Name: | |