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Ltbp1 Antibody (PACO50750)

SKU:
PACO50750
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€339
Frequently bought together:

Description

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Ltbp1 Antibody (PACO50750)

The LTBP1 Polyclonal Antibody (PACO50750) is a valuable tool for researchers studying the latent transforming growth factor beta binding protein 1 (LTBP1). This antibody, raised in rabbits, is highly specific for human samples and has been validated for use in multiple applications, including Western blot and immunohistochemistry.LTBP1 plays a critical role in the regulation of TGF-beta activity, a key signaling molecule involved in cell growth, differentiation, and immune response.

Research into LTBP1 is important for understanding its role in diseases such as cancer, fibrosis, and developmental disorders. The LTBP1 Polyclonal Antibody enables robust detection and analysis of LTBP1 protein expression in various cell types, making it an essential tool for studies in cellular biology and disease mechanisms.

Antibody Name:Ltbp1 Antibody (PACO50750)
Antibody SKU:PACO50750
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA
Recommended Dilutions:
Species Reactivity:Mouse
Immunogen:Recombinant Mouse Latent-transforming growth factor beta-binding protein 1 protein (20-299AA)
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:>95%, Protein G purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Background:May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extra cellular matrix (ECM).
Synonyms:Latent-transforming growth factor beta-binding protein 1 (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1), Ltbp1
UniProt Protein Function:LTBP1: May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extra cellular matrix (ECM). Belongs to the LTBP family. 5 isoforms of the human protein are produced by alternative splicing.Protein type: Chaperone; Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 17|17 E2Cellular Component: cell soma; cytoplasm; dendrite; extracellular matrix; extracellular region; extracellular space; microfibril; mitochondrion; perinuclear region of cytoplasm; protein complex; proteinaceous extracellular matrixMolecular Function: calcium ion binding; growth factor binding; microfibril binding; transforming growth factor beta bindingBiological Process: positive regulation of collagen biosynthetic process; transforming growth factor beta receptor signaling pathway
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q8CG19
NCBI GenInfo Identifier:1063759631
NCBI Gene ID:268977
NCBI Accession:NP_001318166.1
UniProt Secondary Accession:Q8CG19,O88349, Q505C9, Q8BNW7, Q8C7F5, Q8CG18, Q8CIR0 B1B1D9, B1B1E1
UniProt Related Accession:Q8CG19
Molecular Weight:
NCBI Full Name:latent-transforming growth factor beta-binding protein 1 isoform 7
NCBI Synonym Full Names:latent transforming growth factor beta binding protein 1
NCBI Official Symbol:Ltbp1  
NCBI Official Synonym Symbols:Tgfb; Ltbp-1; Ltbp1L; 9830146M04; b2b1000Clo; 9430031G15Rik; TGF-beta1-BP-1  
NCBI Protein Information:latent-transforming growth factor beta-binding protein 1
UniProt Protein Name:Latent-transforming growth factor beta-binding protein 1
UniProt Synonym Protein Names:Transforming growth factor beta-1-binding protein 1; TGF-beta1-BP-1
Protein Family:Latent-transforming growth factor beta-binding protein
UniProt Gene Name:Ltbp1  
UniProt Entry Name:

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