The LTB4R2 Polyclonal Antibody (CAB15479) is a valuable tool for researchers studying the leukotriene B4 receptor 2 (LTB4R2), a G-protein coupled receptor involved in inflammatory responses. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in applications such as Western blotting. By binding to the LTB4R2 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it ideal for investigations in the fields of immunology and inflammation.LTB4R2 is known for its role in mediating leukotriene B4-induced signaling pathways, regulating immune cell recruitment and activation during inflammatory processes.
Understanding the function of LTB4R2 is crucial for developing targeted therapies for conditions characterized by excessive inflammation, such as asthma, rheumatoid arthritis, and inflammatory bowel diseases. By utilizing the LTB4R2 Polyclonal Antibody, researchers can delve deeper into the mechanisms underlying these disorders and explore potential treatment options.
Product Name:
LTB4R2 Rabbit Polyclonal Antibody
SKU:
CAB15479
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 254-358 of human LTB4R2 (NP_062813.2).
Predicted to enable G protein-coupled peptide receptor activity and leukotriene B4 receptor activity. Predicted to be involved in inflammatory response and neuropeptide signaling pathway. Predicted to act upstream of or within keratinocyte migration and signal transduction. Located in nucleoplasm and plasma membrane.
Purification Method:
Affinity purification
Gene ID:
56413
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using LTB4R2 Rabbit pAb (CAB15479).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
