The LTA4H Rabbit Monoclonal Antibody (CAB8918) is specifically designed for research involving LTA4H, an enzyme responsible for the synthesis of leukotriene B4, a lipid mediator involved in inflammatory responses. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications such as Western blot and immunohistochemistry.LTA4H is a key player in the regulation of inflammation and immune responses, making it a promising target for studies in immunology and inflammation-related diseases. By binding to the LTA4H protein, this antibody enables the detection and analysis of LTA4H expression in different cell types, providing valuable insights for research into conditions such as asthma, rheumatoid arthritis, and inflammatory bowel disease.
Research utilizing the LTA4H Rabbit Monoclonal Antibody (CAB8918) can lead to a better understanding of the role of LTA4H in inflammatory pathways and aid in the development of potential therapies targeting this enzyme for the treatment of inflammatory disorders. Its high specificity and sensitivity make it an essential tool for researchers investigating the mechanisms of inflammation and immune regulation.
Product Name:
LTA4H Rabbit Monoclonal Antibody
SKU:
CAB8918
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 501-600 of human LTA4H (P09960).
The protein encoded by this gene is an enzyme that contains both hydrolase and aminopeptidase activities. The hydrolase activity is used in the final step of the biosynthesis of leukotriene B4, a proinflammatory mediator. The aminopeptidase activity has been shown to degrade proline-glycine-proline (PGP), a neutrophil chemoattractant and biomarker for chronic obstructive pulmonary disease (COPD). Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
4048
Clone Number:
ARC1351
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using LTA4H Rabbit mAb (CAB8918) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
