The LTA4H Polyclonal Antibody (CAB14022) is a valuable tool for researchers studying LTA4H, a protein involved in the production of leukotriene B4, a potent inflammatory mediator. This antibody, raised in rabbits, is highly specific to human samples and is suitable for use in various applications, including Western blotting.LTA4H is a key enzyme in the arachidonic acid pathway and is crucial for the production of leukotriene B4, which plays a role in inflammation and immune response. Dysregulation of LTA4H has been implicated in various inflammatory diseases, making it a target for therapeutic intervention.
By using the LTA4H Polyclonal Antibody, researchers can detect and study the expression of LTA4H in different cell types and tissues, providing insights into its function and potential roles in disease pathology. This antibody is a valuable tool for studies in immunology, inflammation, and drug development, as it enables accurate and reliable detection of LTA4H protein levels. Unlock the potential of LTA4H research with the CAB14022 Polyclonal Antibody from Assay Genie.
Product Name:
LTA4H Rabbit Polyclonal Antibody
SKU:
CAB14022
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 312-611 of human LTA4H (NP_000886.1).
The protein encoded by this gene is an enzyme that contains both hydrolase and aminopeptidase activities. The hydrolase activity is used in the final step of the biosynthesis of leukotriene B4, a proinflammatory mediator. The aminopeptidase activity has been shown to degrade proline-glycine-proline (PGP), a neutrophil chemoattractant and biomarker for chronic obstructive pulmonary disease (COPD). Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
4048
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using LTA4H antibody (CAB14022) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
