LSM7 Antibody (PACO42326)
- SKU:
- PACO42326
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
LSM7 Antibody (PACO42326)
The LSM7 Antibody (PAC042326) is a polyclonal antibody specifically designed for research involving LSM7, a protein component of the U6 small nuclear ribonucleoprotein involved in pre-mRNA splicing. The antibody, raised in rabbits, shows high reactivity with human samples and has been validated for use in various applications including Western blot and immunofluorescence.LSM7 is essential for the splicing of pre-mRNA and plays a crucial role in regulating gene expression. Dysregulation of LSM7 has been linked to various diseases, making it a key target for research in molecular biology and genetics.
This antibody binds specifically to LSM7, allowing for accurate detection and analysis in different cell types, making it a valuable tool for studies in RNA splicing, gene regulation, and disease pathology. Gain insights into the functions of LSM7 with this reliable antibody and advance your research in the field of molecular biology and genetics.
| Antibody Name: | LSM7 Antibody (PACO42326) |
| Antibody SKU: | PACO42326 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human U6 snRNA-associated Sm-like protein LSm7 protein (2-103AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: LSM7 antibody at 3µg/ml + HepG2 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 12 kDa. Observed band size: 12 kDa. |
 | Immunohistochemistry of paraffin-embedded human testis tissue using PACO42326 at dilution of 1:100. |
| Background: | Binds specifically to the 3'-terminal U-tract of U6 snRNA and is probably a component of the spliceosome. |
| Synonyms: | U6 snRNA-associated Sm-like protein LSm7, LSM7 |
| UniProt Protein Function: | LSM7: Binds specifically to the 3'-terminal U-tract of U6 snRNA. Belongs to the snRNP Sm proteins family. |
| UniProt Protein Details: | Protein type:Spliceosome; RNA splicing Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: spliceosome; cytosol Molecular Function:protein binding; U6 snRNA binding Biological Process: RNA splicing; gene expression; mRNA processing; mRNA catabolic process, deadenylation-dependent decay |
| NCBI Summary: | Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Apr 2004] |
| UniProt Code: | Q9UK45 |
| NCBI GenInfo Identifier: | 10720075 |
| NCBI Gene ID: | 51690 |
| NCBI Accession: | Q9UK45.1 |
| UniProt Related Accession: | Q9UK45 |
| Molecular Weight: | 103 |
| NCBI Full Name: | U6 snRNA-associated Sm-like protein LSm7 |
| NCBI Synonym Full Names: | LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| NCBI Official Symbol: | LSM7Â Â |
| NCBI Official Synonym Symbols: | YNL147WÂ Â |
| NCBI Protein Information: | U6 snRNA-associated Sm-like protein LSm7 |
| UniProt Protein Name: | U6 snRNA-associated Sm-like protein LSm7 |
| Protein Family: | Sm-like protein |
| UniProt Gene Name: | LSM7Â Â |
| UniProt Entry Name: | LSM7_HUMAN |
| Antibodies |
| LSM7 Antibody (PACO10304) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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