LSM7 Antibody (PACO10304)
- SKU:
- PACO10304
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
LSM7 Antibody (PACO10304)
The LSM7 Antibody (PAC010304) is a high-quality polyclonal antibody designed for research involving LSM7, a protein involved in RNA metabolism and processing. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it an ideal tool for studies in molecular biology and gene expression.LSM7 is a crucial component of the U6 snRNP complex, which plays a vital role in pre-mRNA splicing and mRNA degradation. Dysregulation of LSM7 has been linked to various diseases, including cancer and neurodegenerative disorders.
Therefore, understanding the function and expression of LSM7 is essential for unraveling the mechanisms underlying these conditions.With its high specificity and sensitivity, the LSM7 Antibody is validated for use in Western blot applications, allowing for the detection and analysis of LSM7 protein levels in different cell types and tissues. Researchers in the fields of molecular biology, genetics, and biochemistry will find this antibody valuable in their studies aimed at elucidating the role of LSM7 in various cellular processes.
| Antibody Name: | LSM7 Antibody (PACO10304) |
| Antibody SKU: | PACO10304 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human LSM7 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae);LSM7;YNL147W ; |
| UniProt Protein Function: | LSM7: Binds specifically to the 3'-terminal U-tract of U6 snRNA. Belongs to the snRNP Sm proteins family. |
| UniProt Protein Details: | Protein type:Spliceosome; RNA splicing Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: spliceosome; cytosol Molecular Function:protein binding; U6 snRNA binding Biological Process: RNA splicing; gene expression; mRNA processing; mRNA catabolic process, deadenylation-dependent decay |
| NCBI Summary: | Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Apr 2004] |
| UniProt Code: | Q9UK45 |
| NCBI GenInfo Identifier: | 10720075 |
| NCBI Gene ID: | 51690 |
| NCBI Accession: | Q9UK45.1 |
| UniProt Related Accession: | Q9UK45 |
| Molecular Weight: | 103 |
| NCBI Full Name: | U6 snRNA-associated Sm-like protein LSm7 |
| NCBI Synonym Full Names: | LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| NCBI Official Symbol: | LSM7Â Â |
| NCBI Official Synonym Symbols: | YNL147WÂ Â |
| NCBI Protein Information: | U6 snRNA-associated Sm-like protein LSm7 |
| UniProt Protein Name: | U6 snRNA-associated Sm-like protein LSm7 |
| Protein Family: | Sm-like protein |
| UniProt Gene Name: | LSM7Â Â |
| UniProt Entry Name: | LSM7_HUMAN |
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