The LSM4 Polyclonal Antibody (CAB5891) is a valuable tool for researchers studying LSM4, a essential protein involved in mRNA splicing and RNA processing. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the LSM4 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it perfect for studies in molecular biology, genetics, and cell biology.
LSM4 is a key component of the mRNA processing machinery, playing a critical role in regulating gene expression and ensuring proper splicing of RNA transcripts. Dysregulation of LSM4 has been implicated in various diseases, including cancer and genetic disorders, making it an important target for research in these areas. Understanding the function of LSM4 is essential for uncovering new therapeutic targets and developing potential treatments for these conditions.
Product Name:
LSM4 Rabbit Polyclonal Antibody
SKU:
CAB5891
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-139 of human LSM4 (NP_036453.1).
WB,1:500 - 1:2000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:
GRP; YER112W; LSM4
Positive Sample:
K-562,293T,Mouse thymus
Conjugate:
Unconjugated
Cellular Localization:
Nucleus.
Calculated MW:
15kDa
Observed MW:
16kDa
This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
25804
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using LSM4 Rabbit pAb (CAB5891) at 1:1500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
