The LSM3 Polyclonal Antibody (CAB13189) is a valuable tool for researchers studying LSM3, a protein involved in mRNA degradation and RNA metabolism. This antibody is produced in rabbits and is highly specific to LSM3 in human samples, making it ideal for Western blot applications. By targeting LSM3, this antibody allows for the detection and analysis of LSM3 protein levels in various cell types, providing insight into its role in gene expression regulation.LSM3 is a key player in mRNA decay pathways and is essential for maintaining proper RNA stability and turnover. Dysregulation of LSM3 has been linked to various diseases, including cancer and neurodegenerative disorders, making it a promising target for therapeutic interventions.
Research on LSM3 is crucial for unraveling the mechanisms underlying these diseases and developing novel treatment strategies that target RNA metabolism.By utilizing the LSM3 Polyclonal Antibody, researchers can advance their understanding of LSM3 function and its implications in disease pathogenesis. This antibody serves as a reliable tool for investigating the role of LSM3 in RNA biology and identifying potential therapeutic targets for a range of disorders.
Product Name:
LSM3 Rabbit Polyclonal Antibody
SKU:
CAB13189
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-102 of human LSM3 (NP_055278.1).
Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.
Purification Method:
Affinity purification
Gene ID:
27258
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using LSM3 Rabbit pAb (CAB13189) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
