The LSM2 Polyclonal Antibody (CAB7988) is a valuable tool for research involving LSM2, a key protein involved in RNA metabolism and processing. This antibody, raised in rabbits, is highly specific for LSM2 and is validated for use in various applications, including Western blot and immunofluorescence. It binds specifically to the LSM2 protein, allowing for precise detection and analysis in different cell types.LSM2 is known for its role in spliceosome assembly and mRNA degradation, making it a crucial player in gene expression regulation.
Its involvement in RNA processing pathways makes LSM2 a target of interest in studies related to RNA biology, gene regulation, and diseases like cancer and neurodegenerative disorders. By understanding the function and regulation of LSM2, researchers can gain insight into these complex biological processes and potentially identify new therapeutic targets.
Product Name:
LSM2 Rabbit Polyclonal Antibody
SKU:
CAB7988
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-95 of human LSM2 (NP_067000.1).
This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 19.
Purification Method:
Affinity purification
Gene ID:
57819
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using LSM2 antibody (CAB7988) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
