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LSM2 Monoclonal Antibody [PAT2B2AT] (CPAB0457)

SKU:
CPAB0457
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2a
Clone:
PAT2B2AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

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LSM2 Monoclonal Antibody [PAT2B2AT] (CPAB0457)

The LSM2 Polyclonal Antibody (CPAB0457) is a valuable tool for researchers studying LSM2, a protein involved in RNA processing and regulation. This antibody, generated in rabbits, demonstrates high specificity and sensitivity towards human samples, allowing for accurate detection and analysis in various experimental settings such as Western blot applications. LSM2 is an essential component of the Sm complex, which is critical for mRNA splicing and maturation. Dysregulation of LSM2 has been associated with various diseases, including cancer and neurodegenerative disorders.

Therefore, studying the function and expression of LSM2 is crucial for understanding its role in these pathological conditions and potentially identifying therapeutic targets.With its ability to specifically bind to LSM2, the CPAB0457 antibody enables researchers to investigate the function and localization of LSM2 in different cell types and tissues. By elucidating the mechanisms of LSM2 in RNA metabolism, this antibody serves as a valuable tool in advancing research in molecular biology, oncology, and neurology.

Product Name:LSM2 Antibody
Product Sku:CPAB0457
Size:5μg
Host Species:Mouse
Immunogen:Anti-human LSM2 mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human LSM2 amino acids 1-95 purified from Ecoli.
Clone:PAT2B2AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:LSM2 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2a
Background:LSM2 is a member of the snRNP Sm proteins family. Sm-like proteins are branded in several organisms based on sequence homology with the Sm protein family. Sm-like proteins hold the Sm sequence motif that is made up of 2 regions separated by a linker of variable length which folds as a loop. The Sm-like proteins are believed to create a steady heteromer present in tri-snRNP particles, which are vital for pre-mRNA splicing. LSM2 binds specifically to the 3'-terminal U-tract of U6 snRNA nad takes part in pre-mRNA splicing.
Synonyms:LSM2 homolog U6 small nuclear RNA associated (S. cerevisiae), Small nuclear ribonuclear protein D homolog, chromosome 6 open reading frame 28, snRNP core Sm-like protein Sm-x5, C6orf28, YBL026W, Protein G7b, snRNP.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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