The LSM12 Polyclonal Antibody (CAB15947) is a powerful tool for research involving LSM12, a key protein involved in RNA processing and gene regulation. Raised in rabbits, this antibody is highly specific to human samples and has been validated for use in Western blot applications. By binding to the LSM12 protein, researchers can accurately detect and analyze its expression in various cell types, making it an essential component for studies in molecular biology and gene expression.LSM12 is a vital component of the spliceosome complex, which plays a crucial role in RNA splicing and processing. Dysregulation of LSM12 has been linked to various diseases, including cancer and neurological disorders, making it a promising target for further research.
Understanding the function and regulation of LSM12 is essential for unraveling the complexities of gene expression and potentially developing targeted therapies for related conditions.In conclusion, the LSM12 Polyclonal Antibody offers researchers a reliable tool for investigating the role of LSM12 in RNA processing and gene regulation. Its high specificity and sensitivity make it an invaluable asset for advancing our understanding of molecular mechanisms underlying disease pathogenesis and identifying potential therapeutic targets.
Product Name:
LSM12 Rabbit Polyclonal Antibody
SKU:
CAB15947
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-195 of human LSM12 (NP_689557.1).
Nicotinic acid adenine dinucleotide phosphate (NAADP) binding protein (PubMed:34362892). Confers NAADP sensitivity to the two pore channel complex (TPCs) by acting as TPC accessory protein necessary for NAADP-evoked Ca(2+) release (PubMed:34362892). ( LSM12_HUMAN,Q3MHD2 )
Purification Method:
Affinity purification
Gene ID:
124801
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using LSM12 Rabbit pAb (CAB15947) at 1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
