The LSM11 Polyclonal Antibody (CAB7516) is a vital tool for research involving LSM11, a key protein involved in RNA metabolism and splicing processes. Designed for use in various experimental techniques such as Western blotting, this antibody is raised in rabbits and exhibits high reactivity with human samples. By specifically binding to the LSM11 protein, researchers can accurately detect and analyze its expression in different cell types, making it an essential component for studies in molecular biology and gene regulation.
LSM11 is a crucial factor in pre-mRNA splicing and mRNA degradation, playing a significant role in maintaining RNA stability and proper gene expression. Its intricate involvement in these processes makes it a promising target for research into RNA-related diseases such as cancer, neurodegenerative disorders, and developmental abnormalities. Unraveling the functions of LSM11 is essential for developing potential therapies that target RNA processing pathways and potentially address various genetic disorders and diseases.
Product Name:
LSM11 Rabbit Polyclonal Antibody
SKU:
CAB7516
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 131-360 of human LSM11 (NP_775762.1).
Enables U7 snRNA binding activity. Involved in positive regulation of G1/S transition of mitotic cell cycle. Located in nuclear body. Part of U7 snRNP and telomerase holoenzyme complex. Implicated in Aicardi-Goutieres syndrome.
Purification Method:
Affinity purification
Gene ID:
134353
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using LSM11 antibody (CAB7516) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
