The LSAMP Polyclonal Antibody (CAB14248) is a powerful tool for researchers studying LSAMP, a cell adhesion molecule with roles in neuronal development and synaptic plasticity. This antibody, produced in rabbits, shows high reactivity with human samples and is validated for Western blot applications. By binding specifically to LSAMP, this antibody enables precise detection and analysis of LSAMP expression in various cell types, making it ideal for studies in neuroscience and neurobiology.LSAMP, or Limbic System-Associated Membrane Protein, is involved in processes like axonal growth and synapse formation, making it a key player in the development and function of the nervous system.
Research on LSAMP is important for understanding how neural circuits are established and how they can be affected in conditions like neurodevelopmental disorders and neurodegenerative diseases. The LSAMP Polyclonal Antibody provides a reliable tool for investigating the role of LSAMP in these contexts and may contribute to the development of novel therapies targeting the nervous system.
Product Name:
LSAMP Rabbit Polyclonal Antibody
SKU:
CAB14248
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 219-315 of human LSAMP (NP_002329.2).
Sequence:
PTIT ESKS NEAT TGRQ ASLK CEAS AVPA PDFE WYRD DTRI NSAN GLEI KSTE GQSS LTVT NVTE EHYG NYTC VAAN KLGV TNAS LVLF RPGS VRGI N
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:1000
Synonyms:
LAMP; IGLON3; LSAMP
Positive Sample:
Mouse brain,Mouse kidney,Rat brain
Conjugate:
Unconjugated
Cellular Localization:
Cell membrane, GPI-anchor, Lipid-anchor.
Calculated MW:
37kDa
Observed MW:
37kDa
This gene encodes a member of the immunoglobulin LAMP, OBCAM and neurotrimin (IgLON) family of proteins. The encoded preproprotein is proteolytically processed to generate a neuronal surface glycoprotein. This protein may act as a selective homophilic adhesion molecule during axon guidance and neuronal growth in the developing limbic system. The encoded protein may also function as a tumor suppressor and may play a role in neuropsychiatric disorders. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.
Purification Method:
Affinity purification
Gene ID:
4045
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using LSAMP antibody (CAB14248) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
