The LRRTM4 Polyclonal Antibody (CAB15898) is a valuable tool for researchers studying LRRTM4, a protein involved in synaptic function and neuronal development. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the LRRTM4 protein, this antibody allows for accurate detection and analysis in various cell types, making it ideal for studies in neuroscience and neurodegenerative diseases.LRRTM4 plays a crucial role in synaptic plasticity and neuronal connectivity, making it a potential target for research into conditions such as Alzheimer's disease, schizophrenia, and autism spectrum disorders.
Understanding the function of LRRTM4 is key to unraveling the mechanisms underlying these disorders and developing targeted therapies to treat them.Overall, the LRRTM4 Polyclonal Antibody (CAB15898) is a reliable tool for researchers looking to explore the role of LRRTM4 in neuronal function and neurologic disorders, providing valuable insights that may lead to advancements in the treatment of various neurological conditions.
Product Name:
LRRTM4 Rabbit Polyclonal Antibody
SKU:
CAB15898
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 310-420 of human LRRTM4 (NP_001269857.1).
Cell junction, Cell membrane, Single-pass type I membrane protein, postsynaptic cell membrane, synapse.
Calculated MW:
67kDa
Observed MW:
80kDa
Predicted to enable heparan sulfate proteoglycan binding activity. Predicted to be involved in regulation of synapse assembly. Predicted to act upstream of or within AMPA glutamate receptor clustering; positive regulation of synapse assembly; and regulation of presynaptic membrane organization. Predicted to be located in postsynaptic membrane. Predicted to be part of AMPA glutamate receptor complex. Predicted to be active in extracellular matrix; extracellular space; and glutamatergic synapse. Predicted to be integral component of postsynaptic density membrane.
Purification Method:
Affinity purification
Gene ID:
80059
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using LRRTM4 Rabbit pAb (CAB15898) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
