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LRRTM2 Antibody (PACO28029)

SKU:
PACO28029
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€359

Description

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LRRTM2 Antibody (PACO28029)

The LRRTM2 Polyclonal Antibody (PAC028029) is a powerful tool for studying LRRTM2, a transmembrane protein known to be involved in synaptic transmission and neuronal development. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it an excellent choice for various research applications, including Western blotting and immunofluorescence.LRRTM2 is a key player in the regulation of excitatory synapse development and function, making it a promising target for studies on neurodevelopmental disorders and neurological diseases. By detecting the presence of LRRTM2 in different cell types and tissues, researchers can gain valuable insights into its role in synaptic plasticity and neuronal connectivity.

Furthermore, the dysregulation of LRRTM2 has been associated with conditions such as autism spectrum disorders and schizophrenia, highlighting the significance of investigating its molecular mechanisms. The use of the LRRTM2 Polyclonal Antibody in research can aid in uncovering the pathophysiological implications of LRRTM2 dysfunction and pave the way for potential therapeutic interventions targeting this protein.

Antibody Name:LRRTM2 Antibody (PACO28029)
Antibody SKU:PACO28029
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA
Recommended Dilutions:
Species Reactivity:Human
Immunogen:Recombinant Human Leucine-rich repeat transmembrane neuronal protein 2 protein (165-422AA)
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:>95%, Protein G purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Background:Involved in the development and maintenance of excitatory synapse in the vertebrate nervous system. Regulates surface expression of AMPA receptors and instructs the development of functional glutamate release sites. Acts as a ligand for the presynaptic receptors NRXN1-A and NRXN1-B.
Synonyms:Leucine-rich repeat transmembrane neuronal protein 2 (Leucine-rich repeat neuronal 2 protein), LRRTM2, KIAA0416 LRRN2
UniProt Protein Function:LRRTM2: Involved in the development and maintenance of excitatory synapse in the vertebrate nervous system. Regulates surface expression of AMPA receptors. Acts as a ligand for the presynaptic receptors NRXN1-A and NRXN1-B. Belongs to the LRRTM family.Protein type: Cell development/differentiation; Membrane protein, integralChromosomal Location of Human Ortholog: 5q31.2
UniProt Protein Details:
NCBI Summary:
UniProt Code:O43300
NCBI GenInfo Identifier:50400808
NCBI Gene ID:26045
NCBI Accession:O43300.3
UniProt Secondary Accession:O43300,Q7L770, A0AVL3, A8K4U9, B7ZLN8
UniProt Related Accession:O43300
Molecular Weight:59,076 Da
NCBI Full Name:Leucine-rich repeat transmembrane neuronal protein 2
NCBI Synonym Full Names:leucine rich repeat transmembrane neuronal 2
NCBI Official Symbol:LRRTM2  
NCBI Official Synonym Symbols:
NCBI Protein Information:leucine-rich repeat transmembrane neuronal protein 2
UniProt Protein Name:Leucine-rich repeat transmembrane neuronal protein 2
UniProt Synonym Protein Names:Leucine-rich repeat neuronal 2 protein
Protein Family:Leucine-rich repeat transmembrane neuronal protein
UniProt Gene Name:LRRTM2  
UniProt Entry Name:LRRT2_HUMAN

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