UniProt Protein Function: | LRRN2: Protein type: Membrane protein, integral; Motility/polarity/chemotaxisChromosomal Location of Human Ortholog: 1q32.1Cellular Component: integral to membraneMolecular Function: receptor activityBiological Process: signal transduction; cell adhesion |
UniProt Protein Details: | |
NCBI Summary: | The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | O75325 |
NCBI GenInfo Identifier: | 42544231 |
NCBI Gene ID: | 10446 |
NCBI Accession: | NP_006329.2 |
UniProt Secondary Accession: | O75325,Q5T0Y0, Q6UXM0, Q8N182, B2R624 |
UniProt Related Accession: | O75325 |
Molecular Weight: | 78,859 Da |
NCBI Full Name: | leucine-rich repeat neuronal protein 2 |
NCBI Synonym Full Names: | leucine rich repeat neuronal 2 |
NCBI Official Symbol: | LRRN2Â Â |
NCBI Official Synonym Symbols: | GAC1; LRRN5; LRANK1; FIGLER7Â Â |
NCBI Protein Information: | leucine-rich repeat neuronal protein 2; leucine rich repeat neuronal 5; leucine rich and ankyrin repeats 1; leucine-rich repeat neuronal protein 5; glioma amplified on chromosome 1 protein; fibronectin type III, immunoglobulin and leucine rich repeat domain 7 |
UniProt Protein Name: | Leucine-rich repeat neuronal protein 2 |
UniProt Synonym Protein Names: | Glioma amplified on chromosome 1 protein; Leucine-rich repeat neuronal protein 5 |
Protein Family: | Leucine-rich repeat neuronal protein |
UniProt Gene Name: | LRRN2Â Â |
UniProt Entry Name: | LRRN2_HUMAN |