LRRK2 Rabbit Polyclonal Antibody (CAB0859)
- SKU:
- CAB0859
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | LRRK2 Rabbit Polyclonal Antibody |
SKU: | CAB0859 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 750-910 of human LRRK2 (NP_940980.3). |
Sequence: | EKES SPKL VELL LNSG SREQ DVRK ALTI SIGK GDSQ IISL LLRR LALD VANN SICL GGFC IGKV EPSW LGPL FPDK TSNL RKQT NIAS TLAR MVIR YQMK SAVE EGTA SGSD GNFS EDVL SKFD EWTF IPDS SMDS VFAQ SDDL DSEG SEGS FLVK KKSN S |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | PARK8; RIPK7; ROCO2; AURA17; DARDARIN; LRRK2 |
Positive Sample: | Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell projection, Cytoplasm, Cytoplasmic side, Cytoplasmic vesicle, Endoplasmic reticulum, Endosome, Golgi apparatus, Lysosome, Membrane, Mitochondrion, Mitochondrion inner membrane, Mitochondrion matrix, Mitochondrion outer membrane, Perikaryon, Peripheral membrane protein, axon, dendrite, secretory vesicle, synaptic vesicle membrane. |
Calculated MW: | 286kDa |
Observed MW: | 290kDa |
This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.
Purification Method: | Affinity purification |
Gene ID: | 120892 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |