The LRRK1 Polyclonal Antibody (CAB17768) is a valuable tool for researchers studying the LRRK1 protein, known for its involvement in cellular signaling pathways and potential implications in diseases such as Parkinson's. This antibody, produced in rabbits, shows high reactivity with human samples and is validated for use in Western blot applications. By targeting the LRRK1 protein, researchers can gain insights into its functions and roles in various cell types, providing essential information for studies in neurology and related fields.
LRRK1, a member of the leucine-rich repeat kinase family, is a key player in regulating cellular processes and has been linked to neurodegenerative disorders. Investigating the functions of LRRK1 is essential for understanding its potential as a therapeutic target for diseases like Parkinson's and other neurological conditions. The LRRK1 Polyclonal Antibody offers a reliable tool for researchers looking to explore the biological functions and mechanisms of LRRK1 in health and disease.
Product Name:
LRRK1 Rabbit Polyclonal Antibody
SKU:
CAB17768
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 10-90 of human LRRK1 (NP_078928.3).
This gene encodes a multi-domain protein that is a leucine-rich repeat kinase and a GDP/GTP binding protein. The encoded protein is thought to play a role in the regulation of bone mass. Mice lacking a similar gene showed severe osteopetrosis, increased bone mineralization and decreased bone resorption.
Purification Method:
Affinity purification
Gene ID:
79705
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Raji cells, using LRRK1 Rabbit pAb (CAB17768) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
