The LRRC8D Antibody (PACO10294) is a high-quality polyclonal antibody designed for research involving LRRC8D, a protein belonging to the leucine-rich repeat-containing (LRRC) family. LRRC8D is known to be a key component of volume-regulated anion channel (VRAC) complexes, playing a crucial role in cell volume regulation and cellular homeostasis. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in various applications, including Western blotting and immunofluorescence. By binding specifically to LRRC8D, this antibody enables accurate detection and analysis of LRRC8D proteins in different cell types, making it an ideal tool for studying cell volume regulation in physiology and disease.
LRRC8D is particularly relevant in the fields of cell biology, neuroscience, and cancer research, where dysregulation of cell volume homeostasis is a common feature. Understanding the function of LRRC8D and its role in VRAC complexes may provide valuable insights into cellular processes and potential therapeutic targets for conditions related to cell swelling and shrinkage. This antibody is a valuable tool for researchers looking to investigate the intricate mechanisms underlying cell volume regulation and its implications in various pathological conditions.