The LRRC41 Antibody (PAC022386) is an essential tool for researchers studying LRRC41, a protein associated with immune function and inflammation regulation. This polyclonal antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to LRRC41, this antibody enables accurate detection and analysis in a variety of cell types, making it an invaluable resource for studies in immunology and cancer research.LRRC41, also known as Leucine-rich repeat-containing protein 41, is a key player in immune system modulation, with implications in inflammatory diseases, autoimmune disorders, and cancer progression.
By understanding the role of LRRC41 in immune response regulation, researchers can uncover new insights into disease mechanisms and potentially develop novel therapeutic strategies targeting this protein. The LRRC41 Antibody (PAC022386) is a crucial tool for advancing research in these areas and advancing our understanding of immune function.
Antibody Name:
LRRC41 Antibody (PACO22386)
Antibody SKU:
PACO22386
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human LRRC41.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from rat kidney/rat heart cells, using LRRC41 antibody.
Background:
Probable substrate recognition component of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Synonyms:
Leucine-rich repeat-containing protein 41; Protein Muf1;
UniProt Protein Function:
LRRC41: Probable substrate recognition component of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Ubiquitin conjugating systemChromosomal Location of Human Ortholog: 1p34.1Cellular Component: cytoplasm; membrane; nucleusMolecular Function: protein homodimerization activityBiological Process: protein ubiquitination
