The LRRC4 Polyclonal Antibody (CAB10321) is a versatile tool for researchers studying LRRC4, a potential tumor suppressor gene known to modulate cell adhesion and migration. This antibody, produced in rabbits, exhibits strong reactivity with LRRC4 in human samples and is validated for use in Western blot applications. By specifically binding to the LRRC4 protein, researchers can accurately detect and analyze its expression in various cell types, making it an ideal choice for studies in cancer biology and metastasis research.LRRC4, also known as L-Plastin, is a key player in cell adhesion processes and has been implicated in the regulation of tumor growth and invasion.
Understanding the function of LRRC4 is essential for unraveling its role in cancer progression and metastasis, making this antibody a valuable tool for uncovering new insights into tumor biology.Overall, the LRRC4 Polyclonal Antibody (CAB10321) serves as a critical reagent for researchers aiming to elucidate the functional significance of LRRC4 in cancer development and progression, ultimately paving the way for potential therapeutic interventions targeting this protein in cancer treatment.
Product Name:
LRRC4 Rabbit Polyclonal Antibody
SKU:
CAB10321
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 544-653 of human LRRC4 (NP_071426.1).
Cell junction, Membrane, Single-pass type I membrane protein, postsynaptic cell membrane, synapse.
Calculated MW:
73kDa
Observed MW:
73kDa
Predicted to be involved in modulation of chemical synaptic transmission and synapse organization. Predicted to act upstream of or within synapse organization. Predicted to be located in neuron spine and postsynaptic membrane. Predicted to be active in Schaffer collateral - CA1 synapse; glutamatergic synapse; and plasma membrane. Predicted to be integral component of postsynaptic density membrane.
Purification Method:
Affinity purification
Gene ID:
64101
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using LRRC4 antibody (CAB10321) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
