The LRPPRC Polyclonal Antibody (CAB3365) is a valuable tool for researchers studying LRPPRC, a protein involved in various cellular processes including mitochondrial function and gene expression regulation. This antibody, produced in rabbits, is highly specific for human LRPPRC samples and has been extensively validated for Western blot applications.LRPPRC, also known as leucine rich PPR motif-containing protein, is essential for maintaining mitochondrial function and energy production in cells. Dysregulation of LRPPRC has been implicated in various diseases including metabolic disorders and cancer.
By targeting LRPPRC with this antibody, researchers can accurately detect and analyze the protein in different cell types, allowing for further investigation into its role in disease development and progression.Overall, the LRPPRC Polyclonal Antibody (CAB3365) is a powerful tool for researchers interested in unraveling the mysteries of mitochondrial function and gene expression regulation, providing valuable insights into the pathogenesis of diseases and potential therapeutic strategies.
Product Name:
LRPPRC Rabbit Polyclonal Antibody
SKU:
CAB3365
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1041-1394 of human LRPPRC (NP_573566.2).
This gene encodes a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome.
Purification Method:
Affinity purification
Gene ID:
10128
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using LRPPRC Rabbit pAb (CAB3365) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 0.5s.
