The LRPAP1 Polyclonal Antibody (CAB13026) is a research tool designed for studying LRPAP1, a protein involved in the regulation of cholesterol metabolism and endocytosis. This antibody, derived from rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.LRPAP1, also known as low density lipoprotein receptor-related protein-associated protein 1, plays a crucial role in the internalization and trafficking of LDL receptor-related proteins. Its involvement in cellular processes related to lipid metabolism and receptor signaling makes it a key target for studies in the fields of cardiovascular disease, lipid disorders, and neurodegenerative conditions.
By specifically binding to LRPAP1, this polyclonal antibody allows for the detection and analysis of the protein in various cell types, providing researchers with a valuable tool for investigating its function and potential therapeutic implications. Understanding the role of LRPAP1 in cellular processes can contribute to the development of targeted interventions aimed at addressing disorders related to cholesterol homeostasis and receptor-mediated signaling pathways.
Product Name:
LRPAP1 Rabbit Polyclonal Antibody
SKU:
CAB13026
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 35-357 of human LRPAP1 (NP_002328.1).
This gene encodes a protein that interacts with the low density lipoprotein (LDL) receptor-related protein and facilitates its proper folding and localization by preventing the binding of ligands. Mutations in this gene have been identified in individuals with myopia 23. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
4043
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using LRPAP1 Rabbit pAb (CAB13026) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
