The LRP4 Polyclonal Antibody (CAB10172) is a vital tool for researching LRP4, a key protein involved in neuromuscular development and function. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it a reliable choice for Western blot applications. By detecting and binding to LRP4, researchers can investigate its role in various cellular processes, particularly in the context of neurobiology and muscle physiology.LRP4, also known as low-density lipoprotein receptor-related protein 4, is essential for neuromuscular junction formation and maintenance, making it a crucial target for studying neuromuscular disorders such as myasthenia gravis and congenital myasthenic syndromes.
Additionally, LRP4 has been implicated in bone formation and metabolism, offering insights into conditions like osteoporosis and skeletal abnormalities.The LRP4 Polyclonal Antibody is a versatile tool that enables researchers to explore the functions and mechanisms of LRP4 in various physiological and pathological contexts. Understanding the role of LRP4 could pave the way for the development of novel therapeutic strategies for neurodegenerative diseases, muscle disorders, and skeletal abnormalities.
Product Name:
LRP4 Rabbit Polyclonal Antibody
SKU:
CAB10172
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1500-1725 of human LRP4 (NP_002325.2).
This gene encodes a member of the low-density lipoprotein receptor-related protein family. The encoded protein may be a regulator of Wnt signaling. Mutations in this gene are associated with Cenani-Lenz syndrome.
Purification Method:
Affinity purification
Gene ID:
4038
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using LRP4 antibody (CAB10172) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
