The LRP3 Antibody (PACO04252) is a high-quality polyclonal antibody designed for research involving LRP3, a cell surface receptor implicated in lipid metabolism and inflammation regulation. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot and immunohistochemistry applications. It specifically binds to the LRP3 protein, enabling accurate detection and analysis in various cell types, making it an ideal tool for studies in metabolism, inflammation, and cardiovascular research.
LRP3, also known as lipoprotein receptor-related protein-3, plays a crucial role in lipid homeostasis and the regulation of inflammatory processes. Its involvement in lipid metabolism and inflammation make it a promising target for research into metabolic disorders, cardiovascular diseases, and inflammatory conditions. Understanding the function of LRP3 is essential for developing targeted therapies that can modulate lipid metabolism and inflammation for potential therapeutic applications.
Antibody Name:
LRP3 Antibody
Antibody SKU:
PACO04252
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
synthesized peptide derived from the N-terminal region of human LRP3.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
LRP3: Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear, since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro. Belongs to the LDLR family.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 19q13.11Biological Process: receptor-mediated endocytosis