LRP12 Antibody (PACO14655)
- SKU:
- PACO14655
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
LRP12 Antibody (PACO14655)
The LRP12 Antibody (PAC014655) is a polyclonal antibody designed for research involving LRP12, a protein associated with various cellular functions, including cell signaling and regulation. The antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications. By binding to the LRP12 protein, this antibody enables accurate detection and analysis in a wide range of cell types, making it a valuable tool for studies in molecular biology and cell signaling pathways.
LRP12, also known as Low-Density Lipoprotein Receptor-Related Protein 12, plays a vital role in various cellular processes, including cell growth, differentiation, and migration. Its involvement in signaling pathways makes it a fascinating target for research in areas such as cancer biology and developmental biology. Understanding the function of LRP12 can provide insights into its role in disease development and progression, paving the way for potential therapeutic interventions targeting this protein.
| Antibody Name: | LRP12 Antibody (PACO14655) |
| Antibody SKU: | PACO14655 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Fusion protein of human LRP12 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO14655(LRP12 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO14655(LRP12 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | This gene encodes a member of the low-density lipoprotein receptor related protein family. The product of this gene is a transmembrane protein that is differentially expressed in many cancer cells. Alternate splicing results in multiple transcript variants. |
| Synonyms: | low density lipoprotein receptor-related protein 12 |
| UniProt Protein Function: | LRP12: Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor. Belongs to the LDLR family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 8q22.2 Cellular Component: integral to plasma membrane Molecular Function:protein binding |
| NCBI Summary: | This gene encodes a member of the low-density lipoprotein receptor related protein family. The product of this gene is a transmembrane protein that is differentially expressed in many cancer cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010] |
| UniProt Code: | Q9Y561 |
| NCBI GenInfo Identifier: | 25091287 |
| NCBI Gene ID: | 29967 |
| NCBI Accession: | Q9Y561.1 |
| UniProt Secondary Accession: | Q9Y561,A8K137, B4DRQ2, |
| UniProt Related Accession: | Q9Y561 |
| Molecular Weight: | 93,123 Da |
| NCBI Full Name: | Low-density lipoprotein receptor-related protein 12 |
| NCBI Synonym Full Names: | LDL receptor related protein 12 |
| NCBI Official Symbol: | LRP12Â Â |
| NCBI Official Synonym Symbols: | ST7Â Â |
| NCBI Protein Information: | low-density lipoprotein receptor-related protein 12 |
| UniProt Protein Name: | Low-density lipoprotein receptor-related protein 12 |
| UniProt Synonym Protein Names: | Suppressor of tumorigenicity 7 protein |
| Protein Family: | Low-density lipoprotein receptor-related protein |
| UniProt Gene Name: | LRP12Â Â |
| UniProt Entry Name: | LRP12_HUMAN |
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