LRP12 Antibody (PACO14654)
- SKU:
- PACO14654
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
LRP12 Antibody (PACO14654)
The LRP12 Polyclonal Antibody (PAC014654) is a valuable tool for researchers studying the LRP12 protein, a member of the low-density lipoprotein receptor gene family. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By targeting the LRP12 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in fields such as cardiovascular research, lipid metabolism, and neurobiology.
LRP12, also known as low-density lipoprotein receptor-related protein 12, is involved in various cellular processes, including lipid metabolism regulation and synaptic function. Its role in these pathways suggests potential implications in diseases such as cardiovascular disorders and neurodegenerative conditions. By studying the function of LRP12, researchers can gain insights into its involvement in these diseases and potentially identify new therapeutic targets for intervention.
| Antibody Name: | LRP12 Antibody (PACO14654) |
| Antibody SKU: | PACO14654 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:5000, WB:1:200-1:1000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Fusion protein of human LRP12 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO14654(LRP12 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
 | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human liver cancer tissue, Primary antibody: PACO14654(LRP12 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using PACO14654(LRP12 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | This gene encodes a member of the low-density lipoprotein receptor related protein family. The product of this gene is a transmembrane protein that is differentially expressed in many cancer cells. Alternate splicing results in multiple transcript variants. |
| Synonyms: | low density lipoprotein receptor-related protein 12 |
| UniProt Protein Function: | LRP12: Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor. Belongs to the LDLR family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 8q22.2 Cellular Component: integral to plasma membrane Molecular Function:protein binding |
| NCBI Summary: | This gene encodes a member of the low-density lipoprotein receptor related protein family. The product of this gene is a transmembrane protein that is differentially expressed in many cancer cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010] |
| UniProt Code: | Q9Y561 |
| NCBI GenInfo Identifier: | 25091287 |
| NCBI Gene ID: | 29967 |
| NCBI Accession: | Q9Y561.1 |
| UniProt Secondary Accession: | Q9Y561,A8K137, B4DRQ2, |
| UniProt Related Accession: | Q9Y561 |
| Molecular Weight: | 93,123 Da |
| NCBI Full Name: | Low-density lipoprotein receptor-related protein 12 |
| NCBI Synonym Full Names: | LDL receptor related protein 12 |
| NCBI Official Symbol: | LRP12Â Â |
| NCBI Official Synonym Symbols: | ST7Â Â |
| NCBI Protein Information: | low-density lipoprotein receptor-related protein 12 |
| UniProt Protein Name: | Low-density lipoprotein receptor-related protein 12 |
| UniProt Synonym Protein Names: | Suppressor of tumorigenicity 7 protein |
| Protein Family: | Low-density lipoprotein receptor-related protein |
| UniProt Gene Name: | LRP12Â Â |
| UniProt Entry Name: | LRP12_HUMAN |
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