The LRIT1 Polyclonal Antibody (PAC063899) is a valuable tool for researchers studying LRIT1, a protein involved in the visual transduction process in the retina. This antibody is raised in rabbits and is highly reactive with human samples, making it ideal for Western blot applications. By binding to the LRIT1 protein, this antibody enables the detection and analysis of LRIT1 in various cell types, allowing for in-depth research in the field of vision and eye health.LRIT1 is essential for the proper functioning of photoreceptor cells in the retina, and its dysfunction has been linked to retinal degenerative diseases such as retinitis pigmentosa.
By studying LRIT1 and its role in visual signaling pathways, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets for treatment.Overall, the LRIT1 Polyclonal Antibody is a valuable tool for researchers interested in understanding the molecular mechanisms of vision and exploring potential treatments for retinal diseases. Its specificity and sensitivity make it a reliable choice for research in the fields of ophthalmology and vision science.
Antibody Name:
LRIT1 Antibody (PACO63899)
Antibody SKU:
PACO63899
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:1000-1:5000
Species Reactivity:
Human
Immunogen:
Recombinant Human Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1 protein (251-456AA)
Western Blot. Positive WB detected in: HL60 whole cell lysate. All lanes: LRIT1 antibody at 1:2000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 69 kDa. Observed band size: 69 kDa.
Background:
Possible role in phototransduction.
Synonyms:
Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1 (Leucine-rich repeat-containing protein 21) (Photoreceptor-associated LRR superfamily protein) (Retina-specific protein PAL), LRIT1, LRRC21 PAL
UniProt Protein Function:
LRIT1: Possible role in phototransduction.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 10q23Cellular Component: integral to endoplasmic reticulum membrane
