Anti-LRIG1 Antibody (CAB12027)
- SKU:
- CAB12027
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Antibody Name: | Anti-LRIG1 Antibody |
Antibody SKU: | CAB12027 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 816-1093 of human LRIG1 (NP_056356.2). |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human |
Positive Samples: | Raji, HeLa |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 816-1093 of human LRIG1 (NP_056356.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | YQTR KKSE EYSV TNTD ETVV PPDV PSYL SSQG TLSD RQET VVRT EGGP QANG HIES NGVC PRDA SHFP EPDT HSVA CRQP KLCA GSAY HKEP WKAM EKAE GTPG PHKM EHGG RVVC SDCN TEVD CYSR GQAF HPQP VSRD SAQP SAPN GPEP GGSD QEHS PHHQ CSRT AAGS CPEC QGSL YPSN HDRM LTAV KKKP MASL DGKG DSSW TLAR LYHP DSTE LQPA SSLT SGSP ERAE AQYL LVSN GHLP KACD ASPE STPL TGQL PGKQ RVPL LLAP KS |
Gene ID: | 26018 |
Uniprot: | Q96JA1 |
Cellular Location: | Membrane, Single-pass type I membrane protein |
Calculated MW: | 116kDa/119kDa |
Observed MW: | 142kDa |
Synonyms: | LRIG1, LIG-1, LIG1 |
Background: |
UniProt Protein Function: | LRIG1: a singhle-pass type I membrane protein that acts as a feedback negative regulator of signaling by receptor tyrosine kinases. Regulates cadherin-dependent contact inhibition. Interacts with EGFR, HER2, -3, and -4. Two isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Protein kinase, regulatory subunit Chromosomal Location of Human Ortholog: 3p14.1 Cellular Component: plasma membrane |
UniProt Code: | Q96JA1 |
NCBI GenInfo Identifier: | 143811415 |
NCBI Gene ID: | 26018 |
NCBI Accession: | Q96JA1.2 |
UniProt Secondary Accession: | Q96JA1,Q6IQ51, Q96CF9, Q9BYB8, Q9UFI4, |
UniProt Related Accession: | Q96JA1 |
Molecular Weight: | 119kDa |
NCBI Full Name: | Leucine-rich repeats and immunoglobulin-like domains protein 1 |
NCBI Synonym Full Names: | leucine rich repeats and immunoglobulin like domains 1 |
NCBI Official Symbol: | LRIG1Â Â |
NCBI Official Synonym Symbols: | LIG1; LIG-1Â Â |
NCBI Protein Information: | leucine-rich repeats and immunoglobulin-like domains protein 1 |
UniProt Protein Name: | Leucine-rich repeats and immunoglobulin-like domains protein 1 |
Protein Family: | Leucine-rich repeats and immunoglobulin-like domains protein |
UniProt Gene Name: | LRIG1Â Â |