The LRIG1 Polyclonal Antibody (CAB10297) is a valuable tool for researchers studying LRIG1, a transmembrane protein involved in cellular signaling and regulation. This antibody, produced in rabbits, exhibits strong reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the LRIG1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it suitable for studies in cancer biology, signal transduction, and cell growth control.
LRIG1 is known for its role in regulating receptor tyrosine kinase signaling, particularly in pathways related to cell proliferation and survival. Its involvement in tumor suppression and modulation of key signaling cascades makes it a promising target for research into cancer therapies and targeted therapies. Understanding LRIG1 activity is crucial for uncovering potential therapeutic strategies for cancer and other diseases characterized by dysregulated cellular signaling pathways.
Product Name:
LRIG1 Rabbit Polyclonal Antibody
SKU:
CAB10297
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 816-1093 of human LRIG1 (NP_056356.2).
Predicted to act upstream of or within several processes, including innervation; otolith morphogenesis; and sensory perception of sound. Predicted to be located in plasma membrane. Predicted to be active in extracellular matrix and extracellular space.
Purification Method:
Affinity purification
Gene ID:
26018
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using LRIG1 antibody (CAB10297) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.