| UniProt Protein Function: | May be involved in coupling signal transduction and vesicle trafficking to enable polarized secretion and/or membrane deposition of immune effector molecules. |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012] |
| UniProt Code: | P50851 |
| NCBI GenInfo Identifier: | 345498499 |
| NCBI Gene ID: | 987 |
| NCBI Accession: | NP_001186211.2 |
| UniProt Secondary Accession: | P50851,Q4W5J4, Q4W5L6, Q8NFQ0, Q9H2U3, Q9H2U4 |
| UniProt Related Accession: | P50851 |
| Molecular Weight: | 317,702 Da |
| NCBI Full Name: | lipopolysaccharide-responsive and beige-like anchor protein isoform 1 |
| NCBI Synonym Full Names: | LPS responsive beige-like anchor protein |
| NCBI Official Symbol: | LRBAÂ Â |
| NCBI Official Synonym Symbols: | BGL; LBA; CDC4L; CVID8; LAB300Â Â |
| NCBI Protein Information: | lipopolysaccharide-responsive and beige-like anchor protein |
| UniProt Protein Name: | Lipopolysaccharide-responsive and beige-like anchor protein |
| UniProt Synonym Protein Names: | Beige-like protein; CDC4-like protein |
| Protein Family: | Lipopolysaccharide-responsive and beige-like anchor protein |
| UniProt Gene Name: | LRBAÂ Â |
| UniProt Entry Name: | |
