LRAT Rabbit Polyclonal Antibody (CAB13175)
- SKU:
- CAB13175
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | LRAT Rabbit Polyclonal Antibody |
SKU: | CAB13175 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 31-150 of human LRAT (NP_004735.2). |
Sequence: | GEDK GRNS FYET SSFH RGDV LEVP RTHL THYG IYLG DNRV AHMM PDIL LALT DDMG RTQK VVSN KRLI LGVI VKVA SIRV DTVE DFAY GANI LVNH LDES LQKK ALLN EEVA RRAE KLLG |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | LCA14; LRAT |
Positive Sample: | HT-29,22Rv1,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Endoplasmic reticulum membrane, Endosome, Rough endoplasmic reticulum, Single-pass membrane protein, multivesicular body, perinuclear region. |
Calculated MW: | 26kDa |
Observed MW: | 50-54kDa |
The protein encoded by this gene localizes to the endoplasmic reticulum, where it catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester. This reaction is an important step in vitamin A metabolism in the visual system. Mutations in this gene have been associated with early-onset severe retinal dystrophy and Leber congenital amaurosis 14. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 9227 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |