The LPXC Antibody (PACO34762) is a highly specific and sensitive tool for researchers studying the LPXC protein. LPXC is a key enzyme involved in bacterial lipid A biosynthesis, making it an important target for understanding bacterial cell wall structure and function. The antibody, raised in rabbits, is validated for use in various applications including Western blot and immunohistochemistry, allowing for precise detection and analysis of LPXC in different sample types.
LPXC is essential for the survival and virulence of many pathogenic bacteria, making it a promising target for developing novel antibiotics and antimicrobial therapies. By studying the function and regulation of LPXC, researchers can gain valuable insights into bacterial pathogenesis and drug resistance mechanisms. The LPXC Antibody is a valuable tool for advancing research in microbiology, infectious diseases, and drug discovery.
Antibody Name:
lpxC Antibody (PACO34762)
Antibody SKU:
PACO34762
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Escherichia coli
Immunogen:
Recombinant Escherichia coli UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase protein (1-305AA)
The key enzyme in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Degraded by FtsH; when the activity of FtsH is reduced too much lipid A and not enough phospholipids are made (both pathways use the same precursor), which is lethal.
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
UniProt Protein Details:
NCBI Summary:
LpxC regulated degradation is facilitated by FtsH. [More information is available at EcoGene: EG10265]. UDP-3-O-acyl-N-acetylglucosamine deacetylase (LpxC) catalyzes the second reaction and the first committed step in lipid A biosynthesis. [More information is available at EcoCyc: EG10265].
