UniProt Protein Function: | latrophilin 3: a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. [provided by RefSeq, Jul 2008]Protein type: Membrane protein, integral; GPCR, family 2; Receptor, GPCR; Membrane protein, multi-passChromosomal Location of Human Ortholog: 4q13.1Cellular Component: axon; integral to plasma membrane; intercellular junctionMolecular Function: calcium ion binding; protein bindingBiological Process: neuron migration; synaptogenesis |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9HAR2 |
NCBI GenInfo Identifier: | 47116772 |
NCBI Gene ID: | 23284 |
NCBI Accession: | Q9HAR2.2 |
UniProt Secondary Accession: | Q9HAR2,O94867, Q9NWK5, E9PE04 |
UniProt Related Accession: | Q9HAR2 |
Molecular Weight: | 164,580 Da |
NCBI Full Name: | Adhesion G protein-coupled receptor L3 |
NCBI Synonym Full Names: | adhesion G protein-coupled receptor L3 |
NCBI Official Symbol: | ADGRL3Â Â |
NCBI Official Synonym Symbols: | CL3; LEC3; CIRL3; LPHN3Â Â |
NCBI Protein Information: | adhesion G protein-coupled receptor L3 |
UniProt Protein Name: | Adhesion G protein-coupled receptor L3 |
UniProt Synonym Protein Names: | Calcium-independent alpha-latrotoxin receptor 3 |
Protein Family: | |
UniProt Gene Name: | ADGRL3Â Â |
UniProt Entry Name: | AGRL3_HUMAN |