| UniProt Protein Function: | LPGAT1: Lysophoshatidylglycerol (LPG) specific acyltransferase that recognizes various acyl-CoAs and LPGs as substrates but demonstrates a clear preference for long chain saturated fatty acyl-CoAs and oleoyl-CoA as acyl donors. Prefers oleoyl-LPG over palmitoyl-LPG as an acyl receptor and oleoyl-CoA over lauroyl-CoA as an acyl donor. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.Protein type: EC 2.3.1.-; Membrane protein, multi-pass; Transferase; Membrane protein, integralChromosomal Location of Human Ortholog: 1q32Cellular Component: cytoplasm; endoplasmic reticulum membrane; membraneMolecular Function: 1-acylglycerol-3-phosphate O-acyltransferase activity; 2-acylglycerol-3-phosphate O-acyltransferase activity |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the lysophospholipid acyltransferase family. The encoded protein catalyzes the reacylation of lysophosphatidylglycerol to phosphatidylglycerol, a membrane phospholipid that is an important precursor for the synthesis of cardiolipin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] |
| UniProt Code: | Q92604 |
| NCBI GenInfo Identifier: | 6136501 |
| NCBI Gene ID: | 9926 |
| NCBI Accession: | Q92604.1 |
| UniProt Secondary Accession: | Q92604,Q53YL2 |
| UniProt Related Accession: | Q92604 |
| Molecular Weight: | 43,089 Da |
| NCBI Full Name: | Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 |
| NCBI Synonym Full Names: | lysophosphatidylglycerol acyltransferase 1 |
| NCBI Official Symbol: | LPGAT1Â Â |
| NCBI Official Synonym Symbols: | NET8; FAM34A; FAM34A1Â Â |
| NCBI Protein Information: | acyl-CoA:lysophosphatidylglycerol acyltransferase 1 |
| UniProt Protein Name: | Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Acyl-CoA:lysophosphatidylglycerol acyltransferase |
| UniProt Gene Name: | LPGAT1Â Â |
| UniProt Entry Name: | LGAT1_HUMAN |
