The LPCAT4 Polyclonal Antibody (CAB14316) is a valuable tool for researchers studying LPCAT4, a key enzyme involved in the metabolism of phospholipids. This antibody, raised in rabbits, has high specificity and sensitivity for detecting LPCAT4 in human samples, making it ideal for use in Western blot applications. By binding to the LPCAT4 protein, this antibody allows for accurate detection and analysis of LPCAT4 expression in various cell types.LPCAT4 is essential for maintaining membrane structure and function, as it catalyzes the conversion of lyso-PC to PC, a crucial step in phospholipid biosynthesis.
Dysregulation of LPCAT4 has been linked to various diseases, including cancer and metabolic disorders. Research on LPCAT4 is important for understanding the role of phospholipid metabolism in these conditions and developing potential therapeutic strategies.Overall, the LPCAT4 Polyclonal Antibody offers researchers a reliable tool for investigating the function and regulation of LPCAT4 in cellular processes and disease pathogenesis. Its versatility and specificity make it a valuable asset for studies in lipid metabolism, cancer biology, and metabolic diseases.
Product Name:
LPCAT4 Rabbit Polyclonal Antibody
SKU:
CAB14316
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 345-524 of human LPCAT4 (NP_705841.2).
Members of the 1-acylglycerol-3-phosphate O-acyltransferase (EC 2.3.1.51) family, such as AGPAT7, catalyze the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA), a precursor in the biosynthesis of all glycerolipids. Both LPA and PA are involved in signal transduction (Ye et al., 2005 [PubMed 16243729]).
Purification Method:
Affinity purification
Gene ID:
254531
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using LPCAT4 Rabbit pAb (CAB14316) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
