The LPCAT3 Polyclonal Antibody (CAB17604) is a valuable tool for researchers studying LPCAT3, a key enzyme involved in the biosynthesis of phospholipids. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to LPCAT3, this antibody allows for the detection and analysis of the enzyme in various cell types, making it ideal for studies in lipid metabolism and membrane biogenesis.LPCAT3 plays a crucial role in maintaining cell membrane integrity and function by catalyzing the transfer of fatty acids to lysophospholipids, a process essential for the synthesis of phospholipids.
Dysregulation of LPCAT3 has been implicated in various diseases, including cancer, neurodegenerative disorders, and metabolic diseases. By studying the expression and activity of LPCAT3, researchers can gain insights into its role in disease pathology and potentially identify novel therapeutic targets for these conditions.Overall, the LPCAT3 Polyclonal Antibody is a valuable tool for researchers interested in exploring the role of LPCAT3 in health and disease. Its high specificity and reliability make it an essential component of studies investigating lipid metabolism and membrane biology.
Product Name:
LPCAT3 Rabbit Polyclonal Antibody
SKU:
CAB17604
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 200-300 of human LPCAT3 (NP_005759.4).
Enables 1-acylglycerophosphocholine O-acyltransferase activity; 1-acylglycerophosphoethanolamine O-acyltransferase activity; and 1-acylglycerophosphoserine O-acyltransferase activity. Involved in phosphatidylcholine acyl-chain remodeling; phosphatidylethanolamine acyl-chain remodeling; and phosphatidylserine acyl-chain remodeling. Located in endoplasmic reticulum membrane.
Purification Method:
Affinity purification
Gene ID:
10162
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from HepG2 cells, using LPCAT3 Rabbit pAb (CAB17604) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
