The LPAR5 Monoclonal Antibody (PAC018482) is a valuable tool for researchers studying Lysophosphatidic acid receptor 5 (LPAR5), a G protein-coupled receptor implicated in various cellular processes, including cell proliferation, migration, and survival. This monoclonal antibody, developed using innovative technologies, specifically targets LPAR5 in human samples and is suitable for use in multiple applications, such as Western blot and immunohistochemistry.LPAR5 plays a crucial role in signal transduction pathways associated with cancer progression, making it a promising target for cancer research and therapeutic development.
By detecting and analyzing LPAR5 expression in different cell types, this antibody enables researchers to gain insights into the mechanisms underlying cancer biology and identify potential therapeutic strategies that target LPAR5 signaling.With its high specificity and sensitivity, the LPAR5 Monoclonal Antibody (PAC018482) offers a reliable tool for investigating the role of LPAR5 in cancer and other diseases. Its validation for various research applications makes it an invaluable asset for scientists studying the intricate cellular pathways governed by LPAR5 and its potential as a therapeutic target.
Antibody Name:
LPAR5 Antibody (PACO18482)
Antibody SKU:
PACO18482
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human LPAR5
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO18482(LPAR5 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
This gene encodes a member of the rhodopsin class of G protein-coupled transmembrane receptors. This protein transmits extracellular signals from lysophosphatidic acid, to cells through heterotrimeric G proteins and mediates numerous cellular processes. Many G protein receptors serve as targets for pharmaceutical drugs. Transcript variants of this gene have been described.
Synonyms:
lysophosphatidic acid, receptor 5
UniProt Protein Function:
GPR92: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR; GPCR, family 1Chromosomal Location of Human Ortholog: 12p13.31Cellular Component: integral to membrane; plasma membraneMolecular Function: G-protein coupled receptor activityBiological Process: G-protein coupled receptor protein signaling pathway
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the rhodopsin class of G protein-coupled transmembrane receptors. This protein transmits extracellular signals from lysophosphatidic acid to cells through heterotrimeric G proteins and mediates numerous cellular processes. Many G protein receptors serve as targets for pharmaceutical drugs. Transcript variants of this gene have been described.[provided by RefSeq, Dec 2008]
