LOXL2 Rabbit Monoclonal Antibody (CAB4708)
- SKU:
- CAB4708
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- LOR
- LOR2
- WS9-14
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | LOXL2 Rabbit Monoclonal Antibody |
SKU: | CAB4708 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 675-774 of human LOXL2 (Q9Y4K0). |
Sequence: | NFGD QGIT MGCW DMYR HDID CQWV DITD VPPG DYLF QVVI NPNF EVAE SDYS NNIM KCRS RYDG HRIW MYNC HIGG SFSE ETEK KFEH FSGL LNNQ LSPQ |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | LOR; LOR2; WS9-14; LOXL2 |
Positive Sample: | A-549,PC-3 |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Nucleus, Secreted, basement membrane, extracellular matrix, extracellular space. |
Calculated MW: | 87kDa |
Observed MW: | 100kDa |
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
Purification Method: | Affinity purification |
Gene ID: | 4017 |
Clone Number: | ARC1100 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |