LOXL2 Rabbit Polyclonal Antibody (CAB14638)
- SKU:
- CAB14638
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | LOXL2 Rabbit Polyclonal Antibody |
SKU: | CAB14638 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 51-290 of human LOXL2 (NP_002309.1). |
Sequence: | ANVA KIQL RLAG QKRK HSEG RVEV YYDG QWGT VCDD DFSI HAAH VVCR ELGY VEAK SWTA SSSY GKGE GPIW LDNL HCTG NEAT LAAC TSNG WGVT DCKH TEDV GVVC SDKR IPGF KFDN SLIN QIEN LNIQ VEDI RIRA ILST YRKR TPVM EGYV EVKE GKTW KQIC DKHW TAKN SRVV CGMF GFPG ERTY NTKV YKMF ASRR KQRY WPFS MDCT GTEA HISS CKLG PQVS LDPM KNVT |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:100 - 1:500 |
Synonyms: | LOR; LOR2; WS9-14; LOXL2 |
Positive Sample: | A-549,Mouse heart,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Nucleus, Secreted, basement membrane, extracellular matrix, extracellular space. |
Calculated MW: | 87kDa |
Observed MW: | 100kDa |
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
Purification Method: | Affinity purification |
Gene ID: | 4017 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |